Saccharin

Artificial sweetener 300-500 times sweeter than sugar, one of the oldest.

Source: EFSA 2009 (ADI 5 mg/kg bw/day); FDA 21 CFR 180.37

Also Known As

Regulatory Status

• FDA (US): Permitted Source
• EFSA (EU): ADI established; safe Source
• EU Regulation: Permitted Source
• SFA (Singapore): Permitted Source

Historically linked to bladder tumours in rats at very high doses; mechanism not relevant to humans — IARC delisted, ADI considered safe.